1. Santarossa, C.C., Mickolajczyk, K.J., Steinman, J.B., Urnavicius, L., Chen, N., Hirata, Y., Fukase, Y., Coudray, N., Ekiert, D.C., Bhabha, G., Kapoor, T.M. (2021), Targeting Allostery in the Dynein Motor Domain with Small Molecule Inhibitors. Cell Chemical Biology,  bioRxiv 2020.09.22.308700; doi:
  2. Cupido, T., Jones, N.H., Grasso, M.J., Pisa, R., Kapoor, T.M. (2021) A chemical genetics approach to examine the functions of AAA proteins.  Nature Structural and Molecular Biology, 28, 388-97. PMC33782614. doi:
  3. Wieczorek, M., Ti, S-C., Urnavicius, L., Molloy, K.R., Aher, A., Chait, B.T., Kapoor, T.M. (2021) Biochemical reconstitutions reveal principles of human g-TuRC assembly and function.  Journal of Cell Biology, 220, e202009146.  PMC7844428.  bioRxiv 2020.09.21.306845; doi:
  4. Mickolajczyk, K.J., Shelton, P.M.M., Grasso, M., Cao, X., Warrington, S.E., Aher, A., Liu, S., Kapoor, T.M. (2021) Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.  Biophysical Journal, 120, 1020-30.  PMC7837305.  bioRxiv 2020.07.31.231274; doi: PMC7402037
  5. Carlini, L., Brittingham, G.P., Holt, L.J., Kapoor, T.M. (2020), Microtubules enhance mesoscale effective diffusivity in the crowded metaphase cytoplasm.  Developmental Cell, 54, 574-82.  PMC7685229.
  6. Chen, J., Malone, B., Llewellyn, E., Grasso, M., Shelton, P.M.M., Olinares, P.D.B., Maruthi, K., Eng, E.T., Vatandaslar, H., Chait, B.T., Kapoor, T.M., Darst, S.A., Campbell, E.A. (2020), Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.  Cell, 182, 1560-73.  PMC7386476.  bioRxiv 2020.07.08.194084; doi: PMC7359531
  7. Pisa, R., Kapoor, T.M. (2020), Chemical strategies to overcome resistance against targeted anticancer therapeutics.  Nature Chemical Biology, 16, 817-25.  PMC7510053 [review]
  8. Mickolajczyk, K.J., Olinares, P.D.B., Niu, Y., Chen, N., Warrington, S.E., Sasaki, Y., Walz, T. Chait, B.T., Kapoor, T.M. (2020), Long-range intramolecular allostery and regulation in the dynein-like AAA protein Mdn1.  Proceedings of the National Academy of Science U.S.A., 117, 18459-69.  PMC7414173.
  9. Wieczorek, M., Huang, T-L., Urnavicius, L., Hsia, K-C., Kapoor, T.M. (2020), MZT proteins form multi-faceted structural modules in the γ-tubulin ring complex.  Cell Reports, 31, 107791.  PMC7416306.
  10. Ti, S-C., Wieczorek, M., Kapoor, T.M. (2020), Purification of Affinity Tag-free Recombinant Tubulin from Insect Cells.  STAR Protocols, 1, 100011.  PMC7416841.
  11. Pisa, R., Phua, D.Y.Z., Kapoor, T.M. (2020), Distinct mechanisms of resistance to a CENPE inhibitor emerge in haploid and diploid cells.  Cell Chemical Biology, 27, 850-7.  PMC7444662.
  12. Wieczorek, M., Urnavicius, L., Ti, S-C., Molloy, K.R., Chait, B.T., Kapoor, T.M. (2020), Asymetric molecular architecture of the human γ-tubulin ring complex.  Cell, 180, 165-75.  PMC7027161.  bioRxiv 820142; doi:
  13. Pisa, R., Cupido, T., Steinman, J.B., Jones, N.H., Kapoor, T.M. (2019), Analyzing resistance to design selective chemical inhibitors for AAA proteins.  Cell Chemical Biology, 26, 1263-73.  PMC6754270.
  14. Pamula, M.C., Carlini, L., Forth, S., Verma, P., Suresh, S., Legant, W.R., Khodjakov, A., Betzig, E., Kapoor, T.M. (2019), High-resolution imaging reveals how the spindle midzone impacts chromosome movement.  Journal of Cell Biology, 218, 2529-44.  PMC6683753.
  15. Pisa, R., Cupido, T., Kapoor, T.M. (2019), Designing allele-specific inhibitors of spastin, a microtubule-severing AAA protein.  Journal of the American Chemical Society, 141, 5602-6.  PMC6637947.
  16. Steinman, J.B., Kapoor, T.M. (2019), Using chemical inhibitors to probe AAA protein conformational dynamics and cellular functions.  Current Opinion in Chemical Biology, 50, 1-10.  PMC6880239 [review]
  17. Cupido, T., Pisa, R., Kelley, M.E., Kapoor, T.M. (2019), Designing a chemical inhibitor of the AAA protein spastin using active site mutations.  Nature Chemical Biology, 15, 444-52.  PMC6558985.
  18. Chen, Z., Suzuki, H., Kobayashi, Y., Wang, A.C., DiMaio, F., Kawashima, S.A., Walz, T., Kapoor, T.M. (2018), Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.  Cell, 175, 822-34.  PMC5775914.
  19. Ti, S.-C., Alushin, G.M., Kapoor, T.M. (2018), Human β-tubulin isotypes regulate microtubule protofilament number and stability.  Developmental Cell, 47, 175-90.  PMC6362463.
  20. Shimamoto, Y., Kapoor, T.M. (2018), Analyzing the micromechanics of the cell division apparatus.  Methods in Cell Biology, 145, 173-90.  PMC6029715 [review]
  21. Kleiner, R.E., Hang, L.E., Molloy, K.R., Chait, B.T., Kapoor, T.M. (2018), A chemical proteomics approach to reveal protein-protein interactions in living cells.  Cell Chemical Biology, 25, 110-20.  PMC5775914.
  22. Kapoor, T.M., Miller, R.M. (2017), Leveraging Chemotype-specific Resistance for Drug Target Identification and Chemical Biology.  Trends in Pharmacological Sciences, 38, 1100-9.  PMC5708298 [review]
  23. Steinman, J.B., Santarossa, C.C., Miller, R.M., Yu, L.S., Serpinskaya, A.S., Furukawa, H., Morimoto, S., Tanaka, Y., Nishitani, M., Asano, M., Zalyte, R., Ondrus, A.E., Johnson, A.G., Ye, F., Nachury, M.V., Fukase, Y., Aso, K., Foley, M.A., Gelfand, V.I., Chen, J.K., Carter, A.P., Kapoor, T.M. (2017), Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.  eLife, 6, e25174.  PMC5478271.
  24. Forth, S., Kapoor, T.M. (2017), The mechanics of microtubule networks in cell division.  Journal of Cell Biology, 216, 1525-31.  PMC5461028 [review]
  25. Kapoor, T.M. (2017), Metaphase Spindle Assembly.  Biology (Basel), 6, pii E8.  PMC5372001 [review]
  26. Kawashima, S.A., Chen, Z., Aoi, Y., Patgiri, A., Kobayashi, Y., Nurse, P, Kapoor, T.M. (2016), Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis.  Cell, 167, 512-524.  PMC5116814  (Highlighted in Nature Chemical Biology, 12, 989)
  27. Kellogg, E.H., Howes, S., Ti, S.C., Ramirez-Aportela, E., Kapoor, T.M., Chacon, P., Nogales, E. (2016), Near-atomic cryo-EM structure of PRC1 bound to the microtubule.  Proceedings of the National Academy of Science U.S.A., 113, 9430-9.  PMC5003279
  28. Pamula, M.C., Ti, S.-C., Kapoor, T.M. (2016), The structured core of human b tubulin confers isotype-specific polymerization properties.  Journal of Cell Biology, 213, 425-33.  PMC4878094
  29. Ti, S.-C., Pamula, M.C., Howes, S.C., Duellberg, C., Cade, N.I., Kleiner, R.E., Forth, S., Surrey, T., Nogales, E., Kapoor, T.M. (2016), Mutations in human tubulin proximal to the kinesin-binding site alter dynamic instability at microtubule plus- and minus-ends.  Developmental Cell, 37, 72-84.  PMC4832424
  30. See, S.K., Hoogendoorn, S., Chung, A.H., Ye, F., Steinman, J.B., Sakata-Kato, T., Miller, R.M., Cupido, T., Zalyte, R., Carter, A.P., Nachury, M.V., Kapoor, T.M., Chen, J.K. (2015), Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity.  ACS Chemical Biology, 11, 53-60.  PMC4715766
  31. Shimamoto, Y., Forth, S., Kapoor, T.M. (2015), Measuring pushing and braking forces generated by ensembles of kinesin-5 crosslinking two microtubules.  Developmental Cell, 34, 669-81. PMC4604754
  32. Kleiner, R.E., Verma, P., Molloy, K.R., Chait, B.T., Kapoor, T.M. (2015), Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response. Nature Chemical Biology, 11, 807-14. PMC4589150 [review]
  33. Hsia, K.C., Wilson-Kubalek, E.M., Dottore, A., Hao, Q., Tsai, K.L., Forth, S., Shimamoto, Y., Milligan, R.A., Kapoor, T.M. (2014), Reconstitution of the augmin complex provides insights into its architecture and function.  Nature Cell Biology, 16, 852-63.  PMC4244909
  34. Sikirzhytski, V., Magidson, V., Steinman, J.B., He, J., Le Berre, M., Tikhonenko, I., Ault, J.G., McEwen, B.F., Chen, J.K., Sui, H., Piel, M., Kapoor, T.M., Khodjakov, A. (2014), Direct kinetochore-spindle pole connections are not required for chromosome segregation.  Journal of Cell Biology, 206, 231-43.  PMC4107786
  35. He, M., Subramanian, R., Bangs, F., Omelchenko, T., Liem, K.F. Jr., Kapoor, T.M., Anderson, K.V. (2014), The kinesin-4 protein Kif7 regulates mammalian Hedgehog signaling by organizing the cilium tip compartment.  Nature Cell Biology, 16, 663-72.  PMC4085576.
  36. Kasap, C., Elemento, O., Kapoor, T.M. (2014), DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets.  Nature Chemical Biology, 10, 626-8. PMC4123312
  37. Forth, S., Hsia, K.-C., Shimamoto, Y., Kapoor, T.M. (2014), Asymmetric friction of nonmotor MAPs can lead to their directional motion in active microtubule networks.  Cell, 157, 420-32. PMC4015189 (Highlighted in Developmental Cell (29:5-6)
  38. Kashyap, S., Sandler, J., Martinez, E.J., Kapoor, T.M. (2014), Using ‘biased-privileged’ scaffolds to identify lysine methyltransferase inhibitors.  Bioorganic & Medicinal Chemistry, 22, 2253-60. PMC4038709
  39. Takagi, J., Itabashi, T., Suzuki, K., Shimamoto, Y., Kapoor, T.M., Ishiwata, S. (2014), Micromechanics of the Vertebrate Meiotic Spindle Examined by Stretching along the Pole-to-Pole Axis.  Biophysical Journal, 106, 735-40.  PMC3944988
  40. Aoi, Y., Sato, M., Sutani, T., Shirahige, K., Kapoor, T.M., Kawashima, S.A. (2014), Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast.  Cell Cycle, 13, 1327-34.  PMC4049969
  41. Subramanian, R., Kapoor, T.M. (2013), Slipping past the spindle assembly checkpoint.  Nature Cell Biology, 15, 1261-3. [review]
  42. Takagi, J., Itabashi, T., Suzuki, K., Kapoor, T.M., Shimamoto, Y., Ishiwata, S. (2013), Using micromanipulation to analyze control of vertebrate meiotic spindle size.  Cell Reports, 5, 44-50.  PMC4155493
  43. Yi, J., Wu, X., Chung, A.H., Chen, J.K., Kapoor, T.M., Hammer, J.A. (2013), Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.  Journal of Cell Biology, 202, 779-92.  PMC3760611
  44. Kleiner, R.E., Kapoor, T.M. (2013), Bumping Up Kinase Activity with an ATP-Derived Neo-Substrate.  Cell, 154, 716-8.
  45. Kleiner, R.E., Ti, S.C., Kapoor, T.M. (2013), Site-specific chemistry on the microtubule polymer.  Journal of the American Chemical Society, 135, 12520-3.  PMC3967239
  46. Subramanian, R., Ti, S.C., Tan, L., Darst, S.A., Kapoor, T.M. (2013), Marking and measuring single microtubules by PRC1 and kinesin-4.  Cell, 154, 377-90.  PMC3761943 (Highlighted in Developmental Cell (26:118)
  47. Liu, X., Kapoor, T.M., Chen, J.K., Huse, M. (2013), Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II.  Proceedings of the National Academy of Science U. S. A., 110, 11976-81.  PMC3718145
  48. Kawashima, S.A., Takemoto, A., Nurse, P., Kapoor, T.M. (2013), A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation.  Chemistry & Biology, 20, 262-71.  PMC3626098
  49. Li, X., Foley, E.A., Kawashima, S.A., Molloy, K.R., Li, Y, Chait, B.T., Kapoor, T.M. (2013), Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.  Protein Science, 22, 287-95.  PMC3595459
  50. Foley, E.A., Kapoor, T.M. (2013), Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore.  Nature Reviews Molecular Cell Biology, 14, 25-37.  PMC3762224 [review]
  51. Subramanian, R., Kapoor, T.M. (2012), Building complexity: insights into self-organized assembly of microtubule-based architectures.  Developmental Cell, 23, 874-85.  PMC3526950 [review]
  52. Kawashima, S.A., Takemoto, A., Nurse, P., Kapoor, T.M. (2012), Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.  Chemistry & Biology, 19, 893-901.  PMC3589755
  53. Shimamoto, T., Kapoor, T.M. (2012), Microneedle-based analysis of the micromechanics of the metaphase spindle assembled in Xenopus laevis egg extracts.  Nature Protocols, 7, 959-69.  PMC4117203
  54. Firestone, A.J., Weinger, J.S., Maldonado, M., Barlan, K., Langston, L.D., O’Donnell, M., Gelfand, V.I., Kapoor, T.M.*, Chen, J.K.* (2012), Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein.  Nature, 484, 125-9.  PMC3321072  [*Corresponding Authors] (Highlighted in Nature Reviews Drug Discovery (11:354); Nature Chemical Biology (8, 503)
  55. Wacker, S.A., Houghtaling, B.R., Elemento, O., Kapoor, T.M. (2012), Using transcriptome sequencing to identify mechanisms of drug action and resistance.  Nature Chemical Biology, 8, 235-7.  PMC3281560  (Highlighted in SciBx 5(9))
  56. Li, X., Foley, E.A., Molloy, K.R., Li, Y., Chait, B.T., Kapoor, T.M. (2012), Quantitative chemical proteomics approach to identify post-translational modification-mediated protein-protein interactions.  Journal of the American Chemical Society, 134, 1982-5.  PMC3520067
  57. Li, X., Kapoor, T.M. (2011), An Optical Switch for a Motor Protein.  ChemBioChem, 12, 2265-6.  PMC3490446 [review]
  58. Tan, L., Kapoor, T.M. (2011), Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division.  Proceedings of the National Academy of Science U S A, 108, 16675-80.  PMC3189036
  59. Foley, E.A., Maldonado, M., Kapoor, T.M. (2011), Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.  Nature Cell Biology, 13, 1265-71.  PMC3186838
  60. Wacker, S.A., Kashyap, S., Li, X., Kapoor T.M. (2011), Examining the Mechanism of Action of a Kinesin Inhibitor Using Stable Isotope Labeled Inhibitors for Cross-Linking (SILIC).  Journal of the American Chemical Society, 133, 12386-9.  PMC3309614
  61. Shimamoto, Y., Maeda, Y.T., Ishiwata, S., Libchaber, A.J., Kapoor, T.M. (2011), Insights into the micromechanical properties of the metaphase spindle.  Cell, 145, 1062-74.  PMC3124677 (Highlighted in Current Biology 21(18), R688-R690)
  62. Maldonado, M., Kapoor, T.M. (2011), Moving right along: how PP1 helps clear the checkpoint.  Developmental Cell,20, 733-4.  PMC3161496 [review]
  63. Maldonado, M., Kapoor, T.M. (2011), Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation.  Nature Cell Biology, 13, 475-482.  PMC3076698
  64. Weinger, J.S., Qiu, M., Yang, G., Kapoor, T.M. (2011), A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding.  Current Biology, 21, 154-60.  PMC3049310
  65. Shimamoto, Y., Kapoor, T.M. (2010), Mechanoregulation: Cellular seat belts.  Nature, 468, 518-9. [review]
  66. Islam, K., Chin, H.F., Olivares, A.O., Saunders, L.P., De La Cruz, E.M., Kapoor, T.M. (2010), A myosin V inhibitor based on privileged chemical scaffolds.  Angewandte Chemie, 49, 8484-88.  PMC3063097
  67. Subramanian, R., Wilson-Kubalek, E.M., Arthur, C.P., Bick, M.J., Campbell, E.A., Darst, S.A., Milligan, R.A., Kapoor, T.M. (2010), Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein.  Cell. 142, 433-43.  PMC2966277  (Highlighted in Cell, Leading Edge Minireview,142:364-7; Nature Reviews Molecular Cell Biology,11, 602-603)
  68. Tseng, B.S., Tan, L., Kapoor, T.M., Funabiki, H. (2010), Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly.  Developmental Cell. 18, 903-12.  PMC2905387
  69. Wacker, S.A., Kapoor, T.M. (2010), Targeting a kinetochore-associated motor protein to kill cancer cells.  Proceedings of the National Academy of Sciences, U S A. 107, 5699-700. PMC2851886 [review]
  70. Li, X., Kapoor, T.M. (2010), Approach to profile proteins that recognize post-translationally modified histone “tails”. Journal of the American Chemical Society, 132, 2504-5.  PMC2895771
  71. Houghtaling, B.R., Yang, G., Matov, A., Danuser, G., Kapoor, T.M. (2009), Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle.  Proceedings of the National Academy of Science U S A, 106, 15338-43.  PMC2741252
  72. Foley, E.A., Kapoor, T.M. (2009), Chromosome congression: on the bi-orient express.  Nature Cell Biology11, 787-9. [review]
  73. Subramanian, R., Kapoor, T.M. (2009), Meiotic spindle self-organization: one plus one equals only one.  Current Biology, 19, R290-2. [review]
  74. Itabashi, T., Takagi, J., Shimamoto, Y., Onoe, H., Kuwana, K., Shimoyama, I, Gaetz, J., Kapoor, T.M.*, Ishiwata, S.* (2009), Probing the mechanical architecture of the vertebrate meiotic spindle.  Nature Methods, 6, 167-72.  PMC2766809  [*Corresponding authors]
  75. Kapitein, L.C., Kwok, B.H., Weinger, J.S., Schmidt, C.F., Kapoor, T.M.*, Peterman, E.J.* (2008), Microtubule cross-linking triggers the directional motility of kinesin-5.  Journal of Cell Biology, 182, 421-8.  PMC2500128 [*Equal contribution]
  76. Fuller, B.G., Lampson, M.A., Foley, E.A., Rosasco-Nitcher, S., Le, K.V., Tobelmann, P., Brautigan, D.L., Stukenberg, P.T., Kapoor, T.M. (2008), Midzone activation of Aurora B in Anaphase Produces an Intracellular Phosphorylation Gradient.  Nature, 453, 1132-6.  PMC2724008
  77. Loncarek, J, Kisurina-Evgenieva, O, Vinogradova, T., Hergert, P., La Terra, S., Kapoor, T.M.*, Khodjakov, A.* (2007), The centromere geometry essential for keeping mitosis error free is controlled by spindle forces.  Nature, 450, 745-9. [*Corresponding authors]
  78. Yang, G., Houghtaling, B.R., Gaetz, J., Liu, J.Z., Danuser, G., Kapoor, T.M. (2007), Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging.  Nature Cell Biology, 9, 1233-42.  (Featured in Nature Cell Biology, News and Views, 9: 1223-4; Journal of Cell Biology, Research Roundup, 179, 363)
  79. Brennan, I.M., Peters, U., Kapoor, T.M., Straight, A.F. (2007), Polo-like kinase controls vertebrate spindle elongation and cytokinesis.  PLoS One, 2, e409.
  80. Kwok, B.H., Kapoor, T.M. (2007), Microtubule flux: drivers wanted.  Current Opinion in Cell Biology, 19, 36-42. [review]
  81. Peters, U., Cherian, J., Kim, J.H., Kwok, B.H. Kapoor, T.M. (2006), Probing cell-division phenotype space and Polo-like kinase function using small molecules.  Nature Chemical Biology, 2, 618-26.
  82. Lampson, M.A., Kapoor, T.M. (2006), Targeting protein stability with a small molecule.  Cell, 126, 827-9. [review]
  83. Gaetz, J., Gueroui, Z., Libchaber, A. Kapoor, T.M. (2006), Examining how the spatial organization of chromatin signals influences metaphase spindle assembly.  Nature Cell Biology, 8, 924-32. (Featured in Nature Cell Biology, News and Views, 8: 901-2)
  84. Kwok, B.H., Kapitein, L.C., Kim, J.H., Peterman, E.J., Schmidt, C.F. Kapoor, T.M. (2006), Allosteric inhibition of kinesin-5 modulates its processive directional motility.  Nature Chemical Biology, 2, 480-5.
  85. Kapoor, T.M. Lampson, M.A., Hergert, P., Cameron, L., Cimini, D., Salmon, E.D., McEwen, B.F., Khodjakov, A. (2006), Chromosomes can congress to the metaphase place before biorientation.  Science, 311, 388-91.  (Journal Cover; featured in Science (Perspectives, 311: 343-44), Nature (Research Highlights, 439: 373), Journal of Cell Biology (Research Roundup, 172: 482), Nature Cell Biology (News and Views, 8: 308-10), ACS Chemical Biology (Spotlight, 1:4), Nature Reviews Molecular Cell Biology (Research Highlights, 7: 157).
  86. Khodjakov, A., Kapoor, T. (2005), Microtubule flux: what is it good for?  Current Biology, 15, R966-8. [review]
  87. Lampson, M.A., Kapoor, T.M. (2005), Unraveling cell division mechanisms with small-molecule inhibitors.  Nature Chemical Biology, 2, 19-27. [review]
  88. Mitchison, T.J., Maddox, P., Gaetz, J., Groen, A., Shirasu, M., Desai, A., Salmon, E.D., Kapoor, T.M. (2005), Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles.  Molecular Biology of the Cell, 16. 3064-76.
  89. Kapitein, L.C., Peterman, E.J.G., Kwok, B.H., Kim, J.H., Kapoor, T.M.*, Schmidt, C.F.* (2005), The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.  Nature, 434, 114-8.  [*Equal contribution]  (Featured in JCB (Research Roundup, 169:551))
  90. Cochran, J.C., Gatial, J.E. 3rd, Kapoor, T.M., Gilbert, S.P. (2005), Monastrol inhibition of the mitotic kinesin Eg5.  Journal of Biological Chemistry. 280, 12658-67.27.
  91. Marcus, A.I., Peters, U., Thomas, S.L., Garrett, S., Zelnak, A., Kapoor, T.M., Giannakakou, P. (2005), Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.  Journal of Biological Chemistry, 280, 11569-77.
  92. Kapoor, T.M. (2004), Chromosome segregation: Correcting improper attachment. Current Biology, 14, R1011-13. [review]
  93. Lampson, M.A., Kapoor, T.M. (2005), The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments.  Nature Cell Biology,7,93-98.
  94. Mitchison, T.J. Maddox, P., Groen, A., Cameron, L., Perlman, Z., Ohi, R., Desai, A., Salmon, E.D., Kapoor, T.M. (2004), Bipolarization and poleward flux correlate during Xenopus extract spindle assembly.  Molecular Biology of the Cell, 15, 5603-15.
  95. Solecki, D.J., Model, L., Gaetz, J., Kapoor, T.M., Hatten, M.E. (2004), Par6α signaling controls glial-guided neuronal migration.  Nature Neuroscience, 7, 1195-203.
  96. Kwok, B.H., Yang, J.G., Kapoor, T.M. (2004), The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5.  Current Biology, 14, 1783-8.
  97. Gaetz, J., Kapoor, T.M. (2004), Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles.  Journal of Cell Biology, 166, 465-71.
  98. Cochran, J.C., Sontag, C.A., Maliga, Z., Kapoor, T.M., Correia, J.J., Gilbert, S.P. (2004), Mechanistic analysis of the mitotic kinesin Eg5.  Journal of Biological Chemistry. 279, 38861-70.
  99. Lampson, M.A, Renduchintala, K., Khodjakov, A., Kapoor, T.M. (2004), Correcting improper chromosome-spindle attachments during cell division.  Nature Cell Biology, 6, 232-7(Journal Cover, featured in Nature Cell Biology, News and Views, 6: 181-3); Science, Editor’s choice, 303: 1259)
  100. Peters, U., Kapoor, T.M. (2004), New probes for microtubule dynamics.  Chemistry & Biology, 11, 14-5. [review]
  101. Garrett, S., Kapoor, T.M., (2003), Microtubule assembly: catastrophe factors to the rescue.  Current Biology, 13, R810-2. [review]
  102. Canman, J.C., Cameron, L.A., Maddox, P., Straight, A. TirnauerJ.S., Mitchison, T.J., Fang, G., Kapoor, T.M., Salmon, E.D. (2003), Determining the position of the cell division plane.  Nature, 424, 1074-8.  (Journal Cover)
  103. Hotha, S., Yarrow, J.C., Yang, J.G., Garrett, S., Renduchintala, K.V., Mayer, T.U., Kapoor, T.M. (2003), HR22C16: A potent small-molecule probe for the dynamics of cell division.  Angewandte Chemie International Edition, 42, 2379-2382.
  104. Khodjakov, A., Copenagle, L., Gordon, M.B., Compton, D.A., Kapoor, T.M. (2003), Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis.  Journal of Cell Biology, 160, 671-683.  (Journal Cover, featured in JCB 160:624)
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