Since its inception in 2001, the Kapoor laboratory has worked at the intersection of chemistry, cell biology and cancer.


Central to our work is the discovery and structure-guided design of chemical inhibitors, which can serve as fast-acting probes for dynamic cellular processes. Our studies with these chemical inhibitors can also catalyze the development of new chemotherapeutics. We focus on mechanoenzymes (e.g. motor proteins, unfoldases and helicases) and key proteins required for essential processes such as cytoskeleton organization during cell division. We use cutting-edge live cell microscopy, X-ray, cryo-EM and chemistry-based approaches to analyze biology at resolutions ranging from atoms to single human cells.
We are an inclusive, creative, and collaborative research group that is mindful of the impact of our work on society. We are leveraging our expertise in a collaborative chemical biology project to develop therapeutics for COVID-19.

PEOPLE

Amol Aher

Postdoctoral Associate

aaher​(at)rockefeller.edu ​​

Francesca Anson

Postdoctoral Associate

fanson(at)rockefeller.edu

Adi Berman

Graduate Fellow

aberman(at)rockefeller.edu

​Lina Carlini

Postdoctoral Fellow

lcarlini(at)rockefeller.edu

Natalie Jones

Graduate Fellow

njones(at)rockefeller.edu

Megan Elizabeth Kelley

Graduate Fellow

mkelley(at)rockefeller.edu

Keith Mickolajczyk

Postdoctoral Fellow

kmickolajc(at)rockefeller.edu

Yadira Polanco

Laboratory Support Specialist

Eleni Rice

Research Assistant

erice(at)rockefeller.edu

Patrick Shelton

Postdoctoral Associate

pshelton(at)rockefeller.edu

Lauren Vostal

Graduate Student

lvostal(at)rockefeller.edu

Michal Wieczorek

Postdoctoral Fellow

mwieczorek(at)rockefeller.edu

Orlee Zorbaron

Laboratory Administrator

odzorbaron(at)rockefeller.edu