Since its inception in 2001, the Kapoor laboratory has worked at the intersection of chemistry, cell biology, and cancer.


Central to our work is the discovery and structure-guided design of chemical inhibitors, which can serve as fast-acting probes for dynamic cellular processes. Our studies with these chemical inhibitors can also catalyze the development of new chemotherapeutics. We focus on mechanoenzymes (e.g. motor proteins, unfoldases and helicases) and key proteins required for essential processes such as cytoskeleton organization during cell division. We use cutting-edge live cell microscopy, X-ray, cryo-EM and chemistry-based approaches to analyze biology at resolutions ranging from atoms to single human cells.
We are an inclusive, creative, and collaborative research group that is mindful of the impact of our work on society. We are leveraging our expertise in a collaborative chemical biology project to develop therapeutics for COVID-19.

PEOPLE

Amol Aher

Postdoctoral Associate

aaher​(at)rockefeller.edu ​​

Noa Dahan

graduate student

ndahan(at)rockefeller.edu

Tyler Heiss

Postdoctoral Fellow

theiss(at)rockefeller.edu

Nikolay Kornakov

Postdoctoral Fellow

nkornakov(at)rockefeller.edu

Leandro Pimentel

Graduate Student

lpimentel(at)rockefeller.edu

Yadira Polanco

Laboratory Support Specialist

Leishemba K. Thoidingjam

Postdoctoral Associate

lthoidingjam(at)rockefeller.edu

Lauren Vostal

Graduate Student

lvostal(at)rockefeller.edu

Amy Vonk

Administrative Coordinator

kapoorlabadmin(at)rockefeller.edu

Lily Kronenberg

Research Assistant

lkronenberg(at)rockefeller.edu

Arielle Kolodzinski

Graduate Student

akolodzins(at)rockefeller.edu